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Precision Medicine

Precision Medicine

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Ability to administer personal care based on a patient's genetic, social and behavioral characteristics.

Precision Medicine: Products


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  • Covid-19
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  • In Epic App Orchard
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  • AMC
  • Pediatric Facilities
  • ACO
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EpicCare Ambulatory, one of the top ten ambulatory EHRs in the country, specializes in outpatient primary care. The module is used for documenting visits, placing orders, sending prescriptions, and viewing and communicating test results.
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Solutions Primary Care Management Services, Pharmacogenomic Screening & Decision Support Tools
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Our unique approach uses complex assays and treatment algorithms to help your doctor prescribe the right high blood pressure drugs that will work for you. With Geneticure, you’ll discover the personalized physiology and genetics associated with your hypertension that show the function of your heart, kidneys and blood vessels. Our method goes beyond most DNA tests that only look at drug metabolizing enzymes — how much of a drug gets into your bloodstream. Drug metabolizing enzymes are primarily used to help guide the correct dosage, independent of whether or not it’s the right medication in the first place. With Geneticure, you’ll find out which medications might be most likely to work best for you, based not only on drug metabolism, but also enzymes, hormonal pathways, and drug receptors in your DNA. Geneticure has 3 clinical trials on nearly 700 subjects demonstrating clinical and health economic utility, with 5 peer reviewed publications.
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SolutionsPharmacogenomic Screening & Decision Support Tools, Prescription Decision Support Platform, Genomic-based Wellness Tools
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Phosphorus provides comprehensive genetic testing across most specialties, including: cardiology, lipidology, oncology, neurology, obstetrics and gynecology, fertility, reproductive endocrinology, pharmacology, and more. In addition to operating as a reference lab and conducting genetic testing for your patients, we also provide genetic counseling services. Providers that are interested in moving testing in house, can reach out to our company for lab management and in-house opportunities for partnership.
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SolutionsHereditary Risk Assessment, Genomic-based Wellness Tools, Pharmacogenomic Screening & Decision Support Tools
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Using our Geneticure platform, our team of scientists has developed a COVID19 solution, potentially creating an important short-term advance until a vaccine. One of the most common co-morbidities in patients who develop severe illness is hypertension, an area where we have profound expertise in the genetics of the disease and treatment response. Like in hypertension treatment, we have identified genetic influences within the renin-angiotensin-aldosterone system (RAAS) that we believe will be beneficial in predicting the severity of, and guiding treatment for, COVID19 patients. Many companies and academics are tackling this from various angles leaning on their expertise to help save lives and preserve resources, we hope to do the same. Here’s how: COVID-19, like other coronaviruses, bind to and utilize, angiotensin-converting enzyme 2 (ACE2) as a host receptor in order to infect cells resulting in respiratory illness in humans. This is the lock-and-key allowing entry into the cells. As we all have learned, some can carry and transmit the virus without any symptoms, some with mild symptoms, and some with severe enough complications resulting in death. Hypertension can cause changes in the RAAS (as an important counter-regulatory pathway to balance increases in blood pressure) and common blood pressure medications have shown to modulate ACE2 levels in small trials. Several other clinical comorbidities and demographic variables including diabetes, age, and sex have been shown to cause changes in the RAAS in animal models: these are all associated with differences in COVID-19 presentation. Using the data that are available from these patients with varying levels of severity, it is clear that differences in endogenous ACE2 levels may alter the risk of disease transmission along with the degree of severity of disease progression. Not all hypertensives, diabetics, or men develop COVID-19, and many without these factors ultimately develop COVID-19 at varying degrees of severity, suggesting genetics may be one of many factors that is important. Interestingly, there are important potential differences in the importance of ACE2 pre-vs. post-infection. With high ACE2 levels likely being protective for the heart and lungs post-infection. Given this complex relationship: further study is certainly warranted. With our cheek-swab test, we can identify patients who likely have low vs. high ACE2 levels, based on genetic variants important in the RAAS, to triage their risk for disease progression. We are beginning clinical research trials on this. We can also utilize this genetic information to suggest common medication adjustments that can be utilized to reduce ACE2 concentrations, hopefully improving outcomes and saving lives.
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SolutionsPrecision Medicine Tools for Treatment Selection, Virtual Triage Tools for COVID-19, Concierge Solutions for COVID-19
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By InsightRX

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Achieve therapeutic targets and improve sample efficiency. InsightRX Nova standardizes precision dosing across your institution, improving efficacy, minimizing variability, and reducing adverse events—all while lowering blood sampling by up to 50%. Improve model accuracy and stay up to date. InsightRX Nova gives you access to the most up to date, clinically validated models developed by our partners and curated from the literature. In addition, dosing guidance improves over time as we update models using our proprietary human-assisted AI framework and data from the InsightRX network. Capture results and outcomes. InsightRX Nova includes reports on your institution’s target performance compared to national benchmarks or your institutional data. For more powerful analytics, InsightRX Apollo provides dashboards enabling you to understand how targets are being met across drugs, providers, and subpopulations.
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SolutionsClinical Decision Support Systems, Pharmacogenomic Screening & Decision Support Tools, Web-based Pharmacy Operational Solutions
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